Longitudinal spirometric patterns | p Value^{*} | ||||||

Consistent normal | Recurrent restrictive | Inconsistent restrictive | Recurrent obstructive | Inconsistent obstructive | Mixed restrictive/obstructive | ||

(N=913) | (N=69) | (N=62) | (N=155) | (N=54) | (N=115) | ||

Mean±SD age (years) | 44±17 | 62±15 | 55±17 | 60±13 | 55±17 | 64±11 | NA |

Sex: % female | 59.1 | 76.8 | 69.4 | 38.7 | 59.3 | 67.0 | <0.001 |

Obesity: % with BMI ≥30 kg/m^{2} (n=1325) | 6.3 | 15.4 | 16.7 | 3.3 | 9.6 | 12.5 | 0.006 |

Ever smoking: % with ≥1 pack-year (n=1367) | 48.4 | 37.7 | 50.0 | 82.6 | 73.6 | 58.3 | <0.001 |

Physician-confirmed asthma: % positive (n=1366) | 6.4 | 10.3 | 4.8 | 33.5 | 13.0 | 21.7 | <0.001 |

Eosinophilia: % positive (n=1035) | 7.1 | 6.3 | 10.9 | 14.0 | 14.0 | 13.8 | 0.05 |

Total serum IgE in IU/ml: geometric mean (n=1221) | 25.2 | 19.3 | 29.1 | 52.2 | 25.7 | 23.3 | <0.001 |

Mean±SD total follow-up (years) | 12±7 | 7±7 | 10±7 | 9±7 | 10±7 | 11±7 | <0.001 |

N=1368 unless otherwise specified.

No statistical pair comparisons were completed because of the number of groups.

↵* p Value for the comparison across the six groups after adjustment for age.