Table 1

Demographic and clinical characteristics at enrolment of TESAOD participants according to their lung function at enrolment and vital status at January 2005

	Lung function at enrolment			p Value^*
	Normal (N=1505)	Restrictive spirometric pattern (N=249)	Obstructive spirometric pattern (N=294)	p Value^*
Mean±SD age (years)	46±17	60±15	60±15	NA
Sex: % female	56.3	67.1	46.9^† ^‡	<0.001
Obesity: % with BMI ≥30 kg/m² (n=1978)	6.8	13.6^†	6.4^‡	0.004
Years of formal education: % with >12 years	45.8	37.8	32.0	0.27
Ever smoking: % with ≥ 1 pack-year (n=2046)	53.9	50.6	77.1^† ^‡	<0.001
Pack-years: geometric mean among ever smokers (n=1163)	14.1	22.5	28.9^†	0.006
Physician-confirmed asthma: % positive (n=2046)	8.2	14.1^†	23.5^† ^‡	<0.001
Allergy skin tests: % positive (n=2012)	39.7	25.9	31.6	0.28
Eosinophilia: % positive (n=1542)	7.4	9.6	12.8^†	0.01
Total serum IgE in IU/ml: geometric mean (n=1836)	27.5	21.5	37.8^† ^‡	<0.001
Chronic cough and phlegm: % positive	7.7	13.7^†	31.0^† ^‡	<0.001
Shortness of breath with wheezing: % positive (n=2043)	16.9	27.7^†	42.8^† ^‡	<0.001
≥ Grade 2 on the modified MRC dyspnoea scale^†: % positive (n=2038)	9.5	24.0^†	34.9^† ^‡	<0.001
Ever pneumonia: % positive	23.0	40.6^†	39.5^†	<0.001
Ever ‘heart trouble’: % positive	13.8	26.1	20.7	0.36
Ever stroke: % positive	1.1	6.0^†	3.1	0.05
Diabetes: % positive	3.0	7.2	4.4	0.29
Deceased at January 2005: % deceased	46.3	82.7	84.0	NA

N=2048 unless otherwise specified.
Statistical comparisons are completed across the three groups after adjustment for age (p value reported in the last column) as well as between pairs after adjustment for age and Bonferroni correction.
↵* p Value for the comparison across the three groups after adjustment for age.
↵† Significantly different from normal after adjustment for age and Bonferroni correction.
↵‡ Significantly different from restrictive spirometric pattern after adjustment for age and Bonferroni correction.