Clinical characteristics | Respiratory virus (+) n=34 | Respiratory virus (–) n=246 | p Value |
Baseline features | |||
Mean age | 55.7±14.0 | 55.0±15.1 | 0.800 |
Age >65 | 8 (23.5) | 63 (25.6) | 0.794 |
Male, n (%) | 20 (58.8) | 139 (56.5) | 0.798 |
Immunosuppressive state | 20 (58.8) | 110 (44.7) | 0.122 |
Lung transplant recipient | 8 (23.5) | 28 (11.4) | 0.047 |
Haematological malignancy | 5 (14.7) | 34 (13.8) | 0.889 |
Admitted to medical service | 28 (82.4) | 182 (74.0) | 0.291 |
Chest radiograph | |||
Multifocal infiltrates or consolidation | 17 (50.0) | 82 (33.3) | 0.057 |
Diffuse infiltrates | 4 (11.8) | 72 (29.3) | 0.032 |
Focal findings | 4 (11.8) | 23 (9.4) | 0.655 |
BAL testing | |||
BAL done >7 days after hospitalisation | 8 (23.5) | 81 (32.9) | 0.270 |
Sample sent for routine viral detection | 7 (20.6) | 78 (31.7) | 0.186 |
Microbiological findings in BAL fluid | |||
No microorganism detected | 12 (35.3) | 107 (43.5) | 0.365 |
Bacterial/fungal pathogen detected | 13 (38.2) | 84 (34.2) | 0.639 |
Seasonality | |||
Winter–spring season (November–April) | 24 (70.6) | 154 (62.6) | 0.364 |
Summer months (June–August) | 3 (8.8) | 60 (24.4) | 0.042 |
Severity | |||
In-hospital mortality | 7 (20.6) | 64 (26.0) | 0.495 |
On mechanical ventilation | 21 (61.8) | 167 (68.2) | 0.456 |
Requiring oxygen | 31 (91.2) | 230 (93.9) | 0.548 |
Days of ICU stay (median, IQR) | 9 (0–22) | 18 (0–24) | 0.371 |
Days of hospitalisation (median, IQR) | 16 (99–30) | 19.5 (11–35) | 0.237 |
Any use of antibiotics | 34 (100) | 236 (96.3) | 0.256 |
Days of antibiotic use (median, IQR) | 13 (8–28) | 15 (7–28) | 0.655 |
Any use of antifungal agents | 18 (52.9) | 121 (49.2) | 0.682 |
Values are number (percentage of column total), mean±SD or median (IQR) for continuous variables.
BAL, bronchoalveolar lavage.