Univariable and multivariable analysis, by generalised estimating equation models, for mortality in the intensive care unit
Univariable | Multivariable | |||||
OR | 95% CI | p-Value | OR | 95% CI | p-Value | |
Age, per year | 1.017 | 1.013 to 1.020 | <0.001 | 1.011 | 1.006 to 1.015 | <0.001 |
Gender | ||||||
Male | 1 (reference) | |||||
Female | 0.96 | 0.85 to 1.08 | 0.514 | |||
Body mass index by category | ||||||
Underweight | 1 (reference) | |||||
Normal | 0.91 | 0.67 to 1.25 | 0.573 | |||
Overweight | 0.89 | 0.65 to 1.23 | 0.506 | |||
Obese | 0.87 | 0.62 to 1.22 | 0.422 | |||
Severely obese | 0.80 | 0.53 to 1.22 | 0.302 | |||
Simplified acute physiology score, per point | 1.040 | 1.036 to 1.044 | <0.001 | 1.032 | 1.037 to 1.036 | <0.001 |
Reason of mechanical ventilation | ||||||
Postoperative acute respiratory failure | 1 (reference) | 1 | ||||
Asthma | 0.50 | 0.21 to 1.17 | 0.112 | |||
Neuromuscular disease | 0.95 | 0.47 to 1.91 | 0.887 | |||
Trauma | 1.00 | 0.70 to 1.43 | 0.965 | |||
Chronic obstructive pulmonary disease | 1.29 | 0.92 to 1.82 | 0.132 | |||
Congestive heart failure | 1.89 | 1.39 to 2.58 | <0.001 | 1.59 | 1.15 to 2.20 | 0.004 |
Other acute respiratory failure | 2.03 | 1.55 to 2.66 | <0.001 | 1.78 | 1.35 to 2.35 | <0.001 |
Coma | 2.27 | 1.82 to 2.83 | <0.001 | 2.04 | 1.62 to 2.57 | <0.001 |
Aspiration | 2.68 | 1.82 to 3.92 | <0.001 | 2.03 | 1.36 to 3.03 | <0.001 |
Community pneumonia | 2.81 | 2.14 to 3.69 | <0.001 | 2.34 | 1.76 to 3.12 | <0.001 |
Chronic pulmonary disease non-chronic obstructive pulmonary disease | 3.33 | 2.10 to 5.30 | <0.001 | 4.53 | 2.75 to 7.46 | <0.001 |
Hospital pneumonia | 3.52 | 2.45 to 5.06 | <0.001 | 2.93 | 2.01 to 4.28 | <0.001 |
Cardiac arrest | 4.43 | 3.26 to 6.02 | <0.001 | 2.64 | 1.92 to 3.64 | <0.001 |
Sepsis | 5.25 | 4.08 to 6.76 | <0.001 | 3.72 | 2.86 to 4.84 | <0.001 |
Acute respiratory distress syndrome | 5.44 | 3.77 to 7.84 | <0.001 | 4.75 | 3.21 to 7.00 | <0.001 |
Ventilation | ||||||
Invasive ventilation | 1 (reference) | 1 (reference) | ||||
Success non-invasive positive pressure ventilation | 0.33 | 0.23 to 0.46 | <0.001 | 0.39 | 0.27 to 0.57 | <0.001 |
Failed non-invasive positive pressure ventilation | 1.80 | 1.35 to 2.39 | <0.001 | 1.79 | 1.31 to 2.44 | <0.001 |