Mild COPD | Moderate COPD | Severe COPD | Very severe COPD | |
Prevalence per 1000 people in the general population* | 5.1 | 10.7 | 3.0 | 0.5 |
Incidence per 1000 people in the general population* | 0.71 | 0.94 | 0.08 | 0.003 |
Annual decline in FEV1% predicted† | ||||
Smokers | −1.13 | −1.50 | −1.84 | −2.13 |
Ex-smokers | −0.79 | −1.17 | −1.51 | −1.79 |
One-time increase in FEV1% predicted associated with smoking cessation | 0.03 | 2.91 | 5.56 | 7.76 |
Total mortality per 1000 COPD patients in a specific severity stage* | ||||
Smokers | 61 | 73 | 91 | 114 |
Ex-smokers‡ | 51 | 64 | 82 | 104 |
COPD-related healthcare costs (€, 2007) | 318 | 700 | 2389 | 7847 |
EQ-5D utility weights18 | 0.8971 | 0.7551 | 0.7481 | 0.5493 |
↵* Data from the year 2000, the first year of the simulation.
↵† Data presented as the average for men and women with a mean age of 68 years, the mean age of the total Dutch COPD population.
↵‡ Standardised for the gender, age and COPD severity distribution of the smokers.
COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s.