Table 1

Patient characteristics: anthropometric characteristics, blood gases, spirometric values, subdivision of lung volumes and exercise tolerance in patients with pulmonary fibrosis, cystic fibrosis, chronic obstructive pulmonary disease (COPD), healthy control subjects and transplanted patients

Pulmonary fibrosisCystic fibrosisCOPDHealthy controlsTransplanted
n99211016
Age (years)53.89±4.1932.89±3.0554.43±1.0252.20±2.62451.13±2.42
Gender (M/F)4/55/48/135/511/5
Height (cm)170.22±3.87167.78±3.84167.93±1.99172.85±3.50174.56±2.65
Weight (kg)64.21±4.9552.33±3.1758.51±2.2971.32±2.8875.48±3.92
Body mass index (kg/m2)21.98±1.1318.33±0.5720.77±0.7623.92±0.8224.61±0.86
Po2 (kPa)8.19±0.819.00±0.489.05±0.3510.86±0.24
Pco2 (kPa)4.94±0.375.39±0.325.59±0.234.41±0.12
FVC (litres)1.20±0.191.21±0.131.55±0.104.04±0.403.43±0.38
FVC (% predicted)31.71±2.5529.73±3.3445.66±2.50101.80±3.7479.73±5.85
FEV1 (litres)1.17±0.190.77±0.080.58±0.033.35±0.302.79±0.31
FEV1 (% predicted)37.88±3.5622.46±2.8120.77±1.15102.69±3.3579.40±6.46
FEV1/FVC (%)92.40±2.0665.40±4.1031.66±2.0980.84±1.7475.03±2.73
TGV (litres)1.93±0.254.48±0.487.22±0.463.55±0.353.01±0.29
TGV (% predicted)61.67±7.46149.53±13.92241.07±12.73110.81±7.6091.60±8.92
RV (litres)1.50±0.264.16±0.495.69±0.492.44±0.162.05±0.20
RV (% predicted)74.57±13.17253.74±24.89287.50±21.29121.36±6.76103.44±11.74
TLC (litres)2.77±0.345.65±0.548.46±0.486.63±0.575.72±0.46
TLC (% predicted)45.84±3.9696.19±7.63149.54±6.28105.96±4.2787.33±5.92
RV/TLC (%)52.73±5.6572.41±3.0571.83±3.9537.46±1.3936.69±2.96
Maximum workload (W)13.33±5.9525.56±6.0316.67±2.22159.00±17.3582.5±8.8
Maximum workload (% predicted)77.6±3.117.2±3.513.8±2.297.6±5.046.8±5.3
6MW distance (m)199.60±65.97 (n=5)287.00±54.21 (n=5)229.50±26.07 (n=17)
  • F, female, FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; M, male; 6MW, 6 minute walk; RV, residual volume; TGV, thoracic gas volume; TLC, total lung capacity.