Pulmonary fibrosis | Cystic fibrosis | COPD | Healthy controls | Transplanted | |
n | 9 | 9 | 21 | 10 | 16 |
Age (years) | 53.89±4.19 | 32.89±3.05 | 54.43±1.02 | 52.20±2.624 | 51.13±2.42 |
Gender (M/F) | 4/5 | 5/4 | 8/13 | 5/5 | 11/5 |
Height (cm) | 170.22±3.87 | 167.78±3.84 | 167.93±1.99 | 172.85±3.50 | 174.56±2.65 |
Weight (kg) | 64.21±4.95 | 52.33±3.17 | 58.51±2.29 | 71.32±2.88 | 75.48±3.92 |
Body mass index (kg/m2) | 21.98±1.13 | 18.33±0.57 | 20.77±0.76 | 23.92±0.82 | 24.61±0.86 |
Po2 (kPa) | 8.19±0.81 | 9.00±0.48 | 9.05±0.35 | – | 10.86±0.24 |
Pco2 (kPa) | 4.94±0.37 | 5.39±0.32 | 5.59±0.23 | – | 4.41±0.12 |
FVC (litres) | 1.20±0.19 | 1.21±0.13 | 1.55±0.10 | 4.04±0.40 | 3.43±0.38 |
FVC (% predicted) | 31.71±2.55 | 29.73±3.34 | 45.66±2.50 | 101.80±3.74 | 79.73±5.85 |
FEV1 (litres) | 1.17±0.19 | 0.77±0.08 | 0.58±0.03 | 3.35±0.30 | 2.79±0.31 |
FEV1 (% predicted) | 37.88±3.56 | 22.46±2.81 | 20.77±1.15 | 102.69±3.35 | 79.40±6.46 |
FEV1/FVC (%) | 92.40±2.06 | 65.40±4.10 | 31.66±2.09 | 80.84±1.74 | 75.03±2.73 |
TGV (litres) | 1.93±0.25 | 4.48±0.48 | 7.22±0.46 | 3.55±0.35 | 3.01±0.29 |
TGV (% predicted) | 61.67±7.46 | 149.53±13.92 | 241.07±12.73 | 110.81±7.60 | 91.60±8.92 |
RV (litres) | 1.50±0.26 | 4.16±0.49 | 5.69±0.49 | 2.44±0.16 | 2.05±0.20 |
RV (% predicted) | 74.57±13.17 | 253.74±24.89 | 287.50±21.29 | 121.36±6.76 | 103.44±11.74 |
TLC (litres) | 2.77±0.34 | 5.65±0.54 | 8.46±0.48 | 6.63±0.57 | 5.72±0.46 |
TLC (% predicted) | 45.84±3.96 | 96.19±7.63 | 149.54±6.28 | 105.96±4.27 | 87.33±5.92 |
RV/TLC (%) | 52.73±5.65 | 72.41±3.05 | 71.83±3.95 | 37.46±1.39 | 36.69±2.96 |
Maximum workload (W) | 13.33±5.95 | 25.56±6.03 | 16.67±2.22 | 159.00±17.35 | 82.5±8.8 |
Maximum workload (% predicted)7 | 7.6±3.1 | 17.2±3.5 | 13.8±2.2 | 97.6±5.0 | 46.8±5.3 |
6MW distance (m) | 199.60±65.97 (n=5) | 287.00±54.21 (n=5) | 229.50±26.07 (n=17) | – | – |
F, female, FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; M, male; 6MW, 6 minute walk; RV, residual volume; TGV, thoracic gas volume; TLC, total lung capacity.