Sputum phenotype at loss of control (LOC) or 28 days after steroid withdrawal and after fluticasone 1000 μg daily for 28+ days
| Phenotype at LOC or 28 days after steroid withdrawal | Phenotype after fluticasone 1000 μg daily for 28+ days | |||||
| Eosinophilic | Paucigranulocytic | Mixed | Neutrophilic | NA | ||
| Eosinophilic | 63 (67%) | 32 (51%) | 22 (35%) | 2 (3%) | 2 (3%) | 5 (8%) |
| Paucigranulocytic | 29 (31%) | 4 (14%) | 21 (72%) | 0 (0%) | 3 (10%) | 1 (3%) |
| Mixed | 2 (2%) | 1 (50%) | 0 (0%) | 1 (50%) | 0 (0%) | 0 (0%) |
| Neutrophilic | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| All | 94 (100%) | 37 (39%) | 43 (46%) | 3 (3%) | 5 (5%) | 6 (6%) |
Results expressed as n (%).
Eosinophilic: eosinophils ≥2%, neutrophils <61%; Paucigranulocytic: eosinophils <2%, neutrophils <61%; Mixed: eosinophils ≥2%, neutrophils ≥61%; Neutrophilic: eosinophils <2%, neutrophils ≥61%; NA, sputum sample not available after trial of steroid.