Baseline characteristics of the study population
Analysis sample (n = 20) | Randomised (n = 28) | Completed challenge (n = 38) | |
Mean age in years (SD) | 13.2 (2.36) | 13.3 (2.24) | 12.5 (2.49) |
Mean weight in kg (SD) | 41.1 (11.2) | 41.7 (10.6) | 40.9 (11.5) |
Mean height in cm (SD) | 149 (13.9) | 151 (13.8) | 150 (15.9) |
Number of females (%) | 14 (70) | 18 (64) | 21 (55) |
Mean FEV1 in litres (SD) | 1.67 (0.50) | 1.80 (0.57) | 1.76 (0.58) |
Mean FEV1 % predicted (SD) | 64.4 (10.4) | 67.2 (12.0) | 67.5 (11.8) |
Sputum microbiology* | |||
Pseudomonas aeruginosa | 4 (22%) | ||
Staphylococcus aureus | 2 (11%) | ||
Sternotrophomonas maltophilia | 2 (11%) | ||
Aspergillus fumigatus | 5 (28%) |
*Results available for 18 patients in the analysis sample.
FEV1, forced expiratory volume in 1 s.