Wheezing attacks in atopic versus non-atopic patients with asthma
| Wheezing attacks | FeNO (ppb) | ||||
| Atopic (n=108‡) | Atopic vs non-atopic | Non-atopic (n=45‡) | |||
| Geometric mean (95% CI) | p Value* | p Value† | Geometric mean (95% CI) | p Value* | |
| None | 17 (10 to 26) n=18 | Reference | p<0.05 | 10 (6 to 17) n=9 | Reference |
| 1–3 | 34 (28 to 42) n=60 | 1.00 | p<0.001 | 15 (10 to 23) n=21 | 1.00 |
| ≥4 | 48 (35 to 66) n=30 | <0.05 | p<0.001 | 15 (10 to 22) n=15 | 1.00 |
FeNO logarithmically transformed prior to analysis with results being back-transformed to give geometric means, with adjustment for smoking and gender.
↵* p Value for number of wheezing attacks compared with reference group adjusted for multiple comparisons (Bonferroni) using ANCOVA model.
↵† p Value for comparison between atopic and non-atopic patients with asthma using general linear model.
↵‡ Two participants did not provide information on wheeze attacks and were excluded from this analysis.