Correlation of ICM and sweat test results
| ICM parameter | Group | ||||
| CF unlikely | CF | PS-CF diagnostic | PS-CF known | PI-CF known | |
| ΔIsc,carbachol | −0.16 | −0.46 | −0.18 | −0.41 | −0.23 |
| ΔIsc,cAMP/forskolin | 0.03 | −0.41 | −0.59 | 0.02 | −0.09 |
| ΔIsc,histamine | −0.19 | −0.61 | −0.63 | −0.68 | −0.08 |
| Isc,carb+cAMP+hista | −0.16 | −0.61 | −0.70 | −0.59 | −0.18 |
Correlation (Pearson correlation coefficient, r) between ICM chloride secretory responses and sweat chloride concentration is given, as displayed in figure 2A-D and described in the results.
Diagnostic patients were classified into CF unlikely and PS-CF diagnostic according to ICM and extensive CFTR genotype analysis; the CF group includes all subgroups (PS-CF diagnostic, PS-CF known and PI-CF known) together.
CF, cystic fibrosis; ICM, intestinal current measurement; Isc, short-circuit current; PI, pancreatic-insufficient; PS, pancreatic-sufficient.