Table 2

Predictors for development of ARDS on multivariate analysis

OR (95% CI)p Value
Age (per SD)0.75 (0.66 to 0.84)<0.0001
Female1.11 (0.88 to 1.39)0.4
Apache III score* (per SD increase)1.26 (1.10 to 1.44)0.0009
Diabetes0.62 (0.46 to 0.83)0.001
Clinical risk for ARDS
    Septic shock1.70 (1.33 to 2.18)<0.0001
    Direct pulmonary injury3.29 (2.57 to 4.21)<0.0001
Haematological failure (platelets <80×109/l)1.59 (1.17 to 2.17)0.003
Transfusion of red blood cells1.47 (1.16 to 1.85)0.001
Intubated on ICU admission2.44 (1.84 to 3.25)<0.0001
Peak plasma glucose in first 24 h after ICU admission (per unit increase)1.08 (0.78 to 1.49)0.7
Body mass index (per SD increase)1.24 (1.11 to 1.39)0.0001
  • *APACHE III score calculated without the PaO2/FiO2 score.

  • APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; ICU, intensive care unit.