Wheeze patterns defined from the presence/absence (+/−) of asthma/recurrent wheeze at four follow-up stations and the numbers of cases in each wheeze pattern group for each cohort
| Wheeze pattern | Age (years) | RSV (n=46) | Controls (n=92) | |||
| 3 | 7 | 13 | 18 | |||
| Never wheeze | − | − | − | − | 14 (3, 11)*** | 69 (27, 42) |
| Transient wheeze | + | − | − | − | 7 (5, 2) | 11 (8, 3) |
| Remitting/intermittent | − | − | + | − | 7 (4, 3) | 4 (2, 2) |
| − | + | − | − | |||
| − | + | + | − | |||
| + | + | − | − | |||
| + | + | + | − | |||
| Late onset | − | − | + | + | 4 (1, 3) | 7 (3, 4) |
| − | − | − | + | |||
| Persistent/relapsing | + | + | + | + | 14 (7, 7)*** | 1 (1, 0) |
| + | − | + | + | |||
| − | + | + | + | |||
| + | + | − | + | |||
| + | − | − | + | |||
Male, female distribution shown in parentheses.
Statistical evaluation refers to comparison of proportion of subjects in the different wheeze pattern groups in the RSV and control cohorts: ***p<0.001.
RSV, respiratory syncytial virus.