Table 1

Demographic, functional and inflammatory characteristics of study patients (n=295)

Sex (M/F)131/164
Age, years47.3 (14–83)
Height, cm168.6±9.5
Weight, kg73.16±15.9
Atopy (Y/N)208/87
Smoking (Y/N)58/237
IgE, kU/l169 (53–472)
Blood eosinophils, %3.80±3.4
FEV1, % predicted86±19
FEV1/VC, %75±11
PC20, mg/ml3.32 (0.025–16)
Reversibility, %13.1±12.5
Sputum eosinophils, %1.8 (0.2–9.4)
Sputum neutrophils, %43.6 (17.8–68.8)
FeNO, ppb31 (15–62)
  • Data are presented as mean±SD or median (IQR); PC20 is expressed as geometric mean (range).

  • ACQ, Asthma Control Questionnaire; AQLQ, Asthma Quality of Life Questionnaire; FeNO, exhaled nitric oxide; FEV1, forced expiratory volume in 1 s; PC20, concentration required to provoke a fall in FEV1 of 20% or more; VC, vital capacity.