Incremental and endurance walking capacity, fat-free mass, quadriceps strength and quality of life at baseline and 3 months
| UC (n=26) | PEPR (n=23) | PEPR vs UC | |||
| Baseline | 3 months | Baseline | 3 months | Difference (95% CI), p value* | |
| Weight (kg) | 79.8 (20.3) | 80.2 (19.9) | 77.7 (23.3) | 77.8 (22.7) | −0.2 (−2.5 to 2.1), p=0.86 |
| FFM (kg) | 49.1 (10.5) | 49.9 (11.2) | 48.9 (8.3) | 49.5 (8.3) | −0.2 (1.8 to 1.4), p=0.78 |
| QMVC (kg) | 25.6 (13.1) | 24.4 (13.2) | 22.3 (7.2) | 26.2 (8.9) | 5.1 (2.5 to 7.6), p<0.01 |
| ISW (m) | 165 (96) | 183 (98) | 147 (98) | 216 (126) | 51 (22 to 79), p<0.01 |
| Borg score (0–10) | 3.9 (1.8) | 3.7 (1.7) | 4.2 (2.0) | 4.4 (1.5) | 0.4 (−0.7 to 1.6), p=0.48 |
| Leg fatigue (0–10) | 3.5 (2.6) | 3.5 (2.3) | 2.2 (2.2) | 2.7 (2.5) | 0.5 (−0.7 to 1.7), p=0.38 |
| ESW (m) | 224 (175) | 224 (133) | 214 (402) | 402 (400) | 189 (28 to 350), p=0.02 |
| Borg score (0–10) | 3.7 (1.3) | 4.0 (1.9) | 4.2 (1.8) | 4.3 (1.6) | −0.2 (−1.7 to 1.3), p=0.81 |
| Leg fatigue (0–10) | 3.8 (2.1) | 3.2 (1.9) | 2.6 (2.2) | 2.9 (2.4) | 0.9 (−0.6 to 2.3), p=0.23 |
| SGRQ Symptoms | 75.3 (16.5) | 77.6 (15.5) | 75.6 (16.0) | 74.9 (15.4) | −2.8 (−10.0 to 4.5), p=0.44 |
| SGRQ Activities | 72.0 (18.3) | 76.2 (15.4) | 79.5 (18.1) | 69.6 (19.4) | −10.0 (−19.0 to −1.0), p=0.03 |
| SGRQ Impacts | 43.5 (20.7) | 48.0 (19.3) | 49.4 (18.5) | 43.2 (15.8) | −7.5 (−16.6 to 1.6), p=0.10 |
| SGRQ Total | 57.4 (16.8) | 61.4 (14.7) | 64.1 (16.9) | 56.5 (13.7) | −8.2 (−15.1 to −1.3), p=0.02 |
| CRDQ Dyspnoea | 2.3 (1.1) | 2.5 (0.9) | 2.3 (0.8) | 3.3 (1.5) | 0.8 (0.1 to 1.5), p=0.03 |
| CRDQ Fatigue | 2.8 (1.3) | 3.1 (1.3) | 3.1 (1.1) | 3.6 (1.4) | 0.3 (−0.3 to 1.0), p=0.34 |
| CRDQ Emotion | 3.6 (1.2) | 3.8 (1.5) | 4.1 (1.1) | 4.8 (1.4) | 0.8 (0 to 1.7), p=0.05 |
| CRDQ Mastery | 3.3 (1.6) | 4.0 (1.6) | 3.7 (1.4) | 4.5 (1.2) | 0.4 (−0.4 to 1.2), p=0.32 |
| EQ5D VAS | 54 (17) | 61 (15) | 58 (18) | 68 (17) | 5 (−4 to 14), p=0.29 |
↵* ANCOVA.
Within group differences and differences between UC and PEPR groups shown.
CRDQ, Chronic Respiratory Disease Questionnaire; ESW, endurance walking capacity; FFMI, fat-free mass index; ISW, incremental walking capacity; PEPR, post-exacerbation pulmonary rehabilitation; QMVC, quadriceps maximum voluntary contraction; SGRQ, St George Respiratory Questionnaire; UC, usual care; VAS, visual analogue scale.