Table 2

Organ sites of distant metastases and treatment for distant metastasis of 166 patients with resected stage I non-small cell lung cancer with distant metastasis

VariablesSingle organ metastasis (n=106)Multiple organ metastases (n=60)p Value
First organ site of distant metastasis, n (%)0.019
 Lung22 (20.8)13 (21.7)
 Brain31 (29.2)13 (21.7)
 Bone34 (32.1)23 (38.2)
 Liver14 (13.2)1 (1.7)
 Adrenal gland1 (0.9)4 (6.7)
 Others4 (3.8)6 (10.0)
Second organ site of distant metastasis, n (%)NS
 Lung15 (25.0)
 Brain15 (25.0)
 Bone15 (25.0)
 Liver8 (13.3)
 Adrenal gland2 (3.3)
 Others5 (8.4)
Treatment for distant metastasis, n (%)0.009
 None13 (12.3)1 (1.7)
 With surgery9 (8.4)5 (8.3)
  Surgery only62
  Surgery+R/T21
  Surgery+C/T and R/T12
 C/T and/or R/T39 (36.8)40 (66.7)
  C/T only1319
  R/T only2110
  C/T and R/T511
 Unknown45 (42.5)14 (23.3)
  • C/T, chemotherapy; NS, non-significant; R/T, radiotherapy.