Table 1

Characteristics of 166 patients with resected stage I non-small cell lung cancer with distant metastasis

VariablesSingle organ metastasis (n=106)Multiple organ metastases (n=60)p Value
Age at initial operation, years (mean±SD)65.8±8.964.4±9.00.328
Age at recurrence, years (mean±SD)67.2±9.265.4±9.10.239
Sex, n (%)0.051
 Male88 (83.0)42 (70.0)
 Female18 (17.0)18 (30.0)
Smoking index, pack-years (median (IQR))25.0 (0.0−40.0)14.3 (0.0−35.0)0.180
Tumour location, n (%)0.003
 Left lung39 (36.8)9 (15.0)
 Right lung67 (63.2)51 (85.0)
Tumour size, cm (mean±SD)4.4±2.84.3±1.50.772
Histological type, n (%)0.005
 Squamous cell carcinoma36 (33.9)10 (16.7)
 Adenocarcinoma58 (54.7)37 (61.6)
 Bronchioloalveolar carcinoma6 (5.7)1 (1.7)
 Large cell carcinoma6 (5.7)9 (15.0)
 Adenosquamous carcinoma0 (0.0)3 (5.0)
Extent of pulmonary resection, n (%)0.158
 Sublobar resection1 (0.9)1 (1.7)
 Lobectomy87 (82.1)45 (75.0)
 Bilobectomy or pneumonectomy18 (17.0)14 (23.3)
T status, n (%)0.095
 T134 (32.1)12 (20.0)
 T272 (67.9)48 (80.0)
Visceral pleural invasion, n (%)0.016
 Absent88 (83.0)39 (65.0)
 Present16 (15.1)18 (30.0)
 Unknown2 (1.9)3 (5.0)
Disease-free interval, months (median (IQR))12.6 (6.1−21.9)10.6 (5.2−16.4)0.118