Table 4

Multinomial analysis of age at onset of asthma and NPSR1 SNPs under the additive genetic model

SNPOR (95% CI)p ValueOR (95% CI)p Valuep Value interaction
AsthmaOnset asthma ≤14 (n = 141)Onset asthma >14 (n = 146)
rs13452670.83 (0.62 to 1.12)0.21630.77 (0.58 to 1.02)0.06550.5927
rs1844481.71 (1.26 to 2.32)0.00051.36 (1.03 to 1.78)0.02810.1604
rs3249571.75 (1.29 to 2.35)0.00031.27 (0.97 to 1.67)0.08500.0674
rs3249600.64 (0.46 to 0.88)0.00670.79 (0.59 to 1.05)0.10700.1431
rs3249810.54 (0.40 to 0.74)0.00010.81 (0.62 to 1.06)0.13310.0134
rs3254620.60 (0.44 to 0.81)0.00070.86 (0.66 to 1.13)0.27860.0243
Atopic asthmaOnset asthma ≤14 (n = 106)Onset asthma >14 (n = 71)
rs13452670.87 (0.62 to 1.20)0.39310.66 (0.45 to 0.97)0.03480.3142
rs1844481.69 (1.20 to 2.38)0.00251.45 (1.00 to 2.10)0.04810.2887
rs3249571.72 (1.23 to 2.40)0.00151.46 (1.01 to 2.11)0.04690.314
rs3249600.66 (0.46 to 0.94)0.02030.88 (0.60 to 1.28)0.49570.0765
rs3249810.59 (0.42 to 0.83)0.0020.72 (0.50 to 1.04)0.08060.181
rs3254620.61 (0.44 to 0.84)0.0030.76 (0.53 to 1.09)0.13980.1683
  • Model adjusted by country, body mass index, age, sex and smoking status.