Multinomial analysis of age at onset of asthma and NPSR1 SNPs under the additive genetic model
| SNP | OR (95% CI) | p Value | OR (95% CI) | p Value | p Value interaction |
| Asthma | Onset asthma ≤14 (n = 141) | Onset asthma >14 (n = 146) | |||
| rs1345267 | 0.83 (0.62 to 1.12) | 0.2163 | 0.77 (0.58 to 1.02) | 0.0655 | 0.5927 |
| rs184448 | 1.71 (1.26 to 2.32) | 0.0005 | 1.36 (1.03 to 1.78) | 0.0281 | 0.1604 |
| rs324957 | 1.75 (1.29 to 2.35) | 0.0003 | 1.27 (0.97 to 1.67) | 0.0850 | 0.0674 |
| rs324960 | 0.64 (0.46 to 0.88) | 0.0067 | 0.79 (0.59 to 1.05) | 0.1070 | 0.1431 |
| rs324981 | 0.54 (0.40 to 0.74) | 0.0001 | 0.81 (0.62 to 1.06) | 0.1331 | 0.0134 |
| rs325462 | 0.60 (0.44 to 0.81) | 0.0007 | 0.86 (0.66 to 1.13) | 0.2786 | 0.0243 |
| Atopic asthma | Onset asthma ≤14 (n = 106) | Onset asthma >14 (n = 71) | |||
| rs1345267 | 0.87 (0.62 to 1.20) | 0.3931 | 0.66 (0.45 to 0.97) | 0.0348 | 0.3142 |
| rs184448 | 1.69 (1.20 to 2.38) | 0.0025 | 1.45 (1.00 to 2.10) | 0.0481 | 0.2887 |
| rs324957 | 1.72 (1.23 to 2.40) | 0.0015 | 1.46 (1.01 to 2.11) | 0.0469 | 0.314 |
| rs324960 | 0.66 (0.46 to 0.94) | 0.0203 | 0.88 (0.60 to 1.28) | 0.4957 | 0.0765 |
| rs324981 | 0.59 (0.42 to 0.83) | 0.002 | 0.72 (0.50 to 1.04) | 0.0806 | 0.181 |
| rs325462 | 0.61 (0.44 to 0.84) | 0.003 | 0.76 (0.53 to 1.09) | 0.1398 | 0.1683 |
Model adjusted by country, body mass index, age, sex and smoking status.