Table 1

Clinical outcomes pre- and postnebulised colomycin

n=19PrecolomycinPostcolomycin
Mean (SD)Mean (SD)
Exacerbation frequency/year7.8 (3.0)2.7 (2.1)*
Admission frequency/year3.0 (2.7)0.95 (1.1)†
P aeruginosa sputum positivity/year4.2 (2.5)0.5 (0.5)* (eradication n=3‡)
Sputum volume (ml)31 (20.8)14 (13.5)*
FEV1 (litres)1.13 (0.6)1.14 (0.6)

  • ↵* p<0.001;

  • ↵† p=0.002.

  • ↵‡ Eradication=≥2 negative P aeruginosa sputum cultures postcolomycin.

  • FEV1, forced expiratory volume in 1 s.