Reported medications and other variables (%) in infants with recurrent wheezing during the first year of life (n=6127)
| Inhaled BD | ICS | LTRA‡ | URTI in first 3 months | Parental asthma | Frequent sleep disturbance* | Severe episode | Visits to ED | Admissions to hospital | |
| Chile | |||||||||
| Santiago | 99.4 | 56.3 | 5.0 | 68.2 | 13.0 | 18.4 | 55.2 | 65.5 | 22.1 |
| Valdivia | 98.5 | 47.1 | 4.6 | 67.5 | 18.5 | 21.0 | 59.0 | 74.0 | 36.4 |
| Brazil | |||||||||
| Fortaleza† | 87.4 | 23.1 | 0.5 | 52.7 | – | 38.6 | 59.6 | 73.8 | 24.7 |
| Recife† | 94.7 | 28.2 | 3.0 | 56.2 | – | 33.5 | 66.2 | 87.5 | 23.7 |
| Belo Horizonte | 89.4 | 49.8 | 13.3 | 46.8 | 37.8 | 32.8 | 56.3 | 74.3 | 33.1 |
| Belem† | 92.6† | 32.2 | 2.4 | 56.8 | 20.9 | 30.1 | 57.1 | 72.7 | 22.4 |
| Porto Alegre | 92.9 | 54.3 | 13.0 | 28.0 | 30.4 | 37.4 | 71.9 | 83.5 | 33.5 |
| Sao Paulo† | 89.9 | 15.8 | 3.3 | 49.0 | 13.3 | 34.9 | 53.5 | 72.0 | 23.0 |
| Curitiba | 91.3 | 27.4 | 9.4 | 54.0 | 26.2 | 37.6 | 59.4 | 69.3 | 17.2 |
| Colombia | |||||||||
| Barranquilla | 87.7 | 56.4 | 16.7 | 59.7 | 25.6 | 21.0 | 79.7 | 82.0 | 46.8 |
| Mexico | |||||||||
| Merida | 100.0 | 28.1 | 50.0 | 3.1 | 28.2 | 46.9 | 37.5 | 25.0 | 21.9 |
| Venezuela | |||||||||
| Caracas | 92.8 | 77.6 | 43.6 | 60.5 | 43.7 | 21.0 | 74.6 | 70.7 | 34.7 |
| Latin America total, mean (95% CI) | 92.9 (92.2 to 93.6) | 45.0 (43.6 to 46.4) | 11.5 (10.6 to 12.5) | 55.2 (53.9 to 56.5) | 25.0 (23.7 to 26.3) | 29.1 (28.0 to 30.4) | 61.2 (59.9 to 62.4) | 73.3 (72.1 to 74.4) | 28.4 (27.3 to 29.6) |
| Spain | |||||||||
| Bilbao | 76.4 | 31.7 | 14.5 | 27.7 | 15.1 | 9.6 | 29.6 | 47.2 | 8.9 |
| Cartagena | 82.7 | 73.3 | 31.4 | 55.7 | 22.2 | 25.1 | 51.6 | 58.8 | 12.8 |
| La Coruña | 76.9 | 66.1 | 24.0 | 45.4 | 14.2 | 18.0 | 43.4 | 52.5 | 15.3 |
| Valencia | 88.6 | 57.0 | 19.5 | 47.6 | 15.0 | 17.8 | 61.0 | 76.6 | 24.3 |
| The Netherlands | |||||||||
| Zwolle | 62.5 | 45.3 | 21.0 | 62.9 | 17.3 | 23.6 | 48.2 | 44.8 | 13.9 |
| Europe total, mean (95% CI) | 77.1 (73.9 to 80.0) | 54.2 (50.5 to 57.9) | 22.1 (19.1 to 25.5) | 47.4 (43.8 to 51.0) | 17.1 (14.6 to 20.0) | 18.8 (16.2 to 21.8) | 45.6 (42.0 to 49.2) | 54.8 (51.2 to 58.4) | 14.2 (11.8 to 16.9) |
| Total, mean (95% CI) | 91.1 (92.2 to 93.5) | 46.1 (44.8 to 47.4) | 12.9 (12.0 to 13.8) | 54.3 (53.0 to 55.5) | 23.8 (22.7 to 25.0) | 27.9 (26.9 to 29.1) | 59.4 (58.1 to 60.6) | 71.1 (70.0 to 72.3) | 26.8 (25.7 to 27.9) |
↵* Sleep disturbance due to wheezing (more than 1 week per month, every month).
↵† Inhaled corticosteroids not available at primary care centres (public health system).
↵‡ LTRA were not available for free in Latin American centres.
BD, bronchodilators; ED, emergency department; ICS, inhaled corticosteroids; LTRA, leukotriene receptor antagonists; URTI, upper respiratory tract infection.