Table 3

Positive (PPV) and negative (NPV) predictive values (95% CIs) for serology as an indicator of P aeruginosa at any density in bronchoalveolar lavage (BAL) fluid cultures and its presence in oropharyngeal (OP) cultures

	N	Sensitivity	Specificity	PPV	NPV
Multiple P aeruginosa antigens
BAL
Discovery population	76	0.95 (0.85 to 1.0)	0.62 (0.55 to 0.69)	0.23 (0.14 to 0.32)	0.99 (0.97 to 1.0)
Test population	56	0.46 (0.3 to 0.62)	0.82 (0.75 to 0.88)	0.43 (0.27 to 0.58)	0.84 (0.77 to 0.90)
OP
Test population	32	0.32 (0.14 to 0.50)	0.88 (0.79 to 0.96)	0.57 (0.36 to 0.78)	0.76 (0.67 to 0.86)

P aeruginosa exotoxin A
BAL
Discovery population	76	0.90 (0.77 to 1.0)	0.57 (0.5 to 0.64)	0.20 (0.12 to 0.28)	0.98 (0.95 to 1.0)
Test population	55	0.84 (0.72 to 0.96)	0.52 (0.36 to 0.61)	0.34 (0.24 to 0.44)	0.92 (0.85 to 0.98)
OP
Test population	32	0.88 (0.75 to 1.0)	0.55 (0.42 to 0.67)	0.43 (0.30 to 0.57)	0.92 (0.84 to 1.0)