Mean (SD) and *geometric mean (log SD) fold change in parameters from baseline to immediately post-treatment at 12 weeks with between-group differences and 95% CI
| Change from baseline to 3 months | Difference (95% CI) | ||
| Placebo | Erythromycin | ||
| *Coughs/24 h | 0.73 (0.66) | 0.67 (0.29) | 1.1 (0.7 to 1.5) |
| Sputum neutrophils (%) | +6.6 (23) | −10.2 (33) | 16.8 (1.6 to 32.1) |
| *C2 (μmol/l) | 1.1 (0.4) | 1.6 (0.06) | 0.7 (0.4 to 1.3) |
| *C5 (μmol/l) | 1.2 (0.13) | 0.9 (0.25) | 1.3 (0.9 to 2.0) |
| VAS (mm) | +2 (29) | −12 (33) | 10 (−11 to 33) |
| LCQ | +1.8 (3.8) | +1.8 (3.8) | 0 (−2 to 2) |
| *CFU/ml | 1.17 (0.56) | 0.65 (0.69) | 1.8 (0.6 to 5.8) |
| *Sputum IL-8 (ng/ml) | 2.14 (0.69) | 0.75 (0.23) | 2.9 (0.8 to 9.5) |
CFU, bacterial colony forming units; C2, concentration of capsaicin required to induce two coughs; C5, concentration of capsaicin required to induce five coughs; IL-8, interleukin 8; LCQ, Leicester cough questionnaire; VAS, cough visual analogue score.