Table 2

Recurrence-free proportion and clinicopathological characteristics of the entire cohort

CharacteristicNo. of patients (%)Recurrence-free proportion at 5 years (%)Univariate p value
Overall
Age (years)≤651149 (50)69.20.388
>651146 (50)67.9
GenderWomen889 (38)70.50.049*
Men1406 (62)67.4
Smoking habitsNon-smoker790 (34)71.20.008*
Ever smoker1505 (66)67.2
FEV1/FVC (%)≥701726 (75)69.30.038*
<70559 (24)65.9
Not examined10
CEAWithin normal range1441 (63)72<0.001*
Elevated851 (37)62.6
Not examined3
Tumour size (cm)≤3.01239 (54)79.5<0.001*
>3.01056 (46)55.3
Histological typeAdenocarcinoma1546 (67)69.80.009*
Non-adenocarcinoma749 (33)66.1
Histological differentiationWell differentiated628 (27)86.7<0.001*
Moderately/poorly differentiated1667 (73)61
Lymphatic permeationAbsent1595 (69)77.7<0.001*
Present700 (31)49.1
Intratumoral vascular invasionAbsent1151 (50)85<0.001*
Present1144 (50)51.5
Visceral pleural invasionAbsent1537 (67)77.9<0.001*
Present758 (33)48.6
N statusN01640 (71)80.7<0.001*
N1 or N2655 (29)36.8
  • * Indicates significance.

  • Log rank test.

  • CEA, preoperative serum carcinoembryonic antigen level (normal upper limit 5 ng/ml); FEV1/FVC, forced expiratory volume in 1 s to forced vital capacity ratio.