Both CRL and FVC measured (n=283) | Whole cohort | |
Male sex | 51% (143/283) | 51% (912/1797) |
Maternal smoking during pregnancy | 20% (56/283)* | 30% (593/1999) |
History of maternal asthma | 14% (40/283) | 17% (334/1999) |
Mean crown–rump length (SD), mm | 43 (13), n=283 | 44 (13), n=903 |
Mean crown–rump length z-score | 0.65 | 0.72 |
Mean biparietal diameter (SD), mm | 47 (3), n=267 | 48 (3), n=1560 |
Mean biparietal diameter z-score | 0.47 | 0.43 |
Mean femur length (SD), mm | 33 (3), n=261 | 33 (3), n=1544 |
Mean femur length z-score | 0.62 | 0.56 |
Mean gestation at term (range), weeks | 40 (35–42) | 40 (26–42) |
Mean birth weight (SD), g | 3495 (453) | 3502 (476) n=1717 |
Ever wheeze | 23% (64/282) | 20% (235/1192) |
Wheeze in the last 12 months | 15% (41/282) | 13% (150/1195) |
Wheeze without cold in the last 12 months | 7% (21/282) | 7% (78/1195) |
Seen doctor with wheeze in last 12 months | 11% (32/282) | 10% (112/1195) |
Ever asthma | 13% (37/279) | 13% (142/1187) |
Doctor-confirmed asthma | 13% (35/279) | 11% (132/1187) |
Asthma and wheeze in last 12 months | 9% (26/279) | 8% (96/1187) |
Atopic aged 5 years | 28% (73/258) | 25% (175/689) |
Mean FVC z-score | −0.05 (n=283) | 0.02 (n=608) |
↵* p<0.001 for comparison with whole cohort.