Table 3

Median change from baseline to months 3 and 27 for spirometry parameters (combined 28-day and 56-day TIS groups)

Month 3Month 27
FEV1 % predicted0.6 (n=39)–1.3 (n=18)
FVC % predicted–2.7 (n=39)–2.3 (n=18)
FEF25–75 % predicted–0.1 (n=36)0.2 (n=17)
  • FEF25–75, forced expiratory flow between 25% and 75%; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; TIS, tobramycin inhalation solution.