Table 3

Observed and expected deaths from lung cancer for members of the BTS cryptogenic fibrosing alveolitis cohort

NPerson-years at riskObserved deathsExpected deathsSMR (95% CI)
All5832296.30466.217.40 (5.42 to 9.88)
Younger (<68.75 years)293 (50.3%)1423.91282.6110.72 (7.10 to 15.45)
Older (⩾68.75 years)290872.40183.585.02 (2.98 to 7.95)
Men370 (63.5%)1369.62404.938.12 (5.80 to 11.05)
Women213926.6861.284.67 (1.72 to 10.20)
Non-smokers136 (23.3%)516.8220.942.13 (0.26 to 7.69)
Ex-smokers337 (57.8%)1270.76253.986.28 (4.06 to 9.27)
Current smokers110 (18.9%)508.72191.2914.67 (8.83 to 22.92)
Less severe symptoms on presentation*375 (64.4%)1786.28334.756.95 (4.78 to 6.96)
More severe symptoms on presentation†207499.47131.468.93 (4.74 to 15.23)
No reported asbestos exposure494 (85.0%)1967.87355.186.76 (4.71 to 9.40)
Reported asbestos exposure87327.86111.0310.65 (5.32 to 19.06)
Less than “moderate” exposure557 (95.7%)2193.17425.887.15 (5.15 to 9.66)
“Moderate” exposure or more2598.3840.3013.12 (3.57 to 33.59)
Less than 10 years exposure543 (93.5%)2168.52385.786.57 (4.65 to 9.02)
At least 10 years exposure38127.2180.4318.58 (8.03 to 36.66)
  • *Defined as normal exercise grade, breathless up hill and normal pace on level or breathless at normal pace on level.

  • †Defined as breathless when walking 100 yards slowly or breathless at rest.

  • SMR, standardised mortality ratio.