Table 2

Costing for screening using the NICE protocol

NICE protocol (CXR first), 280 immigrants
Step1: CXR if age >11 and not pregnant
Unit costTotal cost
275 CXR£23.24£6393.75
Step 2: TST if pregnant or age <16 (12 individuals) or age 16–35 from sub-Saharan Africa or from country with TB incidence >500/105 (209 individuals)
221 TST£13.69£3025.49
Step 3: QFT if positive TST (estimated TST-positive rate 69%)
153 QFT£25.67£3927.51
Total cost for screening£13 346.75
LTBI cases (estimated QFT-positive rate 54%)83
Cost per case LTBI identified£160.81
  • CXR, chest x ray; LTBI, latent tuberculosis infection; NICE, National Institute for Health and Clinical Excellence; QFT, QuantiFERON-TB Gold; TST, tuberculin skin test.