Table 1

Lung cancer mortality among patients with cryptogenic fibrosing alveolitis (CFA)/idiopathic pulmonary fibrosis (IPF)

StudyType of studyNo of deathsNo of deaths with lung cancerPrevalence of lung cancer (%; 95% CI)
Meyer and Liebow (1965)11Necropsy series19421.1 (6.1 to 45.6)
Turner-Warwick et al (1980)24Case series1552012.9 (8.1 to 19.2)
Wright et al (1981)31Case series31722.6 (9.6 to 41.1)
Tukiainen et al (1983)32Case series4424.5 (0.6 to 15.3)
Kawai et al (1987)33Autopsy case series47817.0 (7.6 to 30.8)
Wells et al (1994)34Case series12764.7 (1.0 to 8.4)
Matsushita et al (1995)1Autopsy case series834048.2 (37.1 to 59.4)
Johnston et al (1997)4Case series2312912.6 (8.6 to 17.5)
Hironaka and Fukayama (1999)6Autopsy case series703245.7 (33.7 to 58.1)
Qunn (2001)7Autopsy case series723143.1 (31.4 to 55.3)
Araki (2003)35Autopsy case series861517.4 (10.1 to 27.1)
Jeon (2006)36Case series5048.0 (2.2 to 19.2)
Okamoto (2006)37Case series561221.4 (11.6 to 34.4)
Daniels (2008)38Autopsy series4200 (0 to 8.4*)
  • *One-sided 97.5% confidence interval.