Treatment end points
| G 0 months | G 12 months | G 15 months | S 0 months | S 12 months | S 15 months | |
| Bacterial density Log10 (CFU/ml) | 8.0 (7.6–8.3) | 3.0 (1.0–5.9)*‡ | 7.3 (5.9–7.8)† | 7.9 (7.3–8.2) | 7.7 (7.2–8.1) | 7.5 (6.5–8.2) |
| FEV1 (litres) | 1.9 (1.6–2.3) | 1.6 (1.5–2.1)* | 1.7 (1.3–2.1) | 1.6 (1.2–2.3) | 1.6 (1.2–2.1) | 1.7 (1.3–2.1) |
| FVC (litres) | 2.8 (2.3–3.4) | 2.5 (2.1–2.9)* | 2.7 (2.2–3.1) | 2.9 (2.1–3.3) | 2.7 (2.2–3.2) | 2.7 (2.2–3.2) |
| ISWT (m) | 350 (270–530) | 510 (360–690)*‡ | 420 (340–580)† | 345 (258–450) | 415 (267–530) | 385 (232–490) |
| Exacerbations | 0 (0–1)‡ | 0 (0–1) | 1.5 (1–2) | 0 (0–1) | ||
| LCQ | 14.1 (11.8–16.2)‡ | 17.7 (14.9–18.3)* | 14.9‡ (11.1–18.1)† | 17.5 (14.9–19.4) | 16.4 (14.0–19.5) | 17.1 (15.5–19.5) |
*p<0.05 when compared with 0 months in group G.
†p<0.05 when compared with month 12 in group G.
‡p<0.05 when comparing group G with group S for all time points.
CFU, colony-formning units; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ISWT, incremental shuttle walk test; LCQ, Leicester Cough Questionnaire.