Severity scale | PSI (n=16 519) | CURB-65 (n=11 199) | CRB-65 (n=8143) | CURB (n=6237) | ||||
Summary statistic (95% CI) | I2 | Summary statistic (95% CI) | I2 | Summary statistic (95% CI) | I2 | Summary statistic (95% CI) | I2 | |
Pooled sensitivity | 0.90 (0.87 to 0.92) | 59% | 0.62 (0.54 to 0.70) | 81% | 0.33 (0.24 to 0.44) | 84% | 0.63 (0.49 to 0.76) | 88% |
Pooled specificity | 0.53 (0.46 to 0.59) | 98% | 0.79 (0.75 to 0.83) | 96% | 0.92 (0.86 to 0.96) | 98% | 0.77 (0.68 to 0.83) | 98% |
Positive predictive value | 0.14 (0.13 to 0.16) | 75% | 0.24 (0.19 to 0.30) | 88% | 0.28 (0.18 to 0.41) | 92% | 0.17 (0.14 to 0.22) | 78% |
Negative predictive value | 0.98 (0.98 to 0.99) | 46% | 0.95 (0.93 to 0.97) | 91% | 0.94 (0.92 to 0.95) | 89% | 0.97 (0.96 to 0.97) | 52% |
Diagnostic OR | 10.77 (8.29 to 13.97) | 39% | 6.40 (5.05 to 8.10) | 56% | 5.97 (3.41 to 10.44) | 86% | 5.75 (4.59 to 7.21) | 0% |
↵* Summary statistics consist of the pooled sensitivity, pooled specificity, positive and negative predictive values and diagnostic OR for the performance of each test in differentiating between survivors and patients who subsequently die.
CRB-65, confusion, respiratory rate, blood pressure, age ≥65 years; CURB, confusion, urea nitrogen, respiratory rate, blood pressure; CRB-65, confusion, respiratory rate, blood pressure, age ≥65 years; CURB, confusion, urea nitrogen, respiratory rate, blood pressure; CURB-65, confusion, urea nitrogen, respiratory rate, blood pressure, age ≥65 years; PSI, Pneumonia Severity Index.