Table 2

Summary statistics* of test performance for the pneumonia risk stratification scales

Severity scalePSI (n=16 519)CURB-65 (n=11 199)CRB-65 (n=8143)CURB (n=6237)
Summary statistic (95% CI)I2Summary statistic (95% CI)I2Summary statistic (95% CI)I2Summary statistic (95% CI)I2
Pooled sensitivity0.90 (0.87 to 0.92)59%0.62 (0.54 to 0.70)81%0.33 (0.24 to 0.44)84%0.63 (0.49 to 0.76)88%
Pooled specificity0.53 (0.46 to 0.59)98%0.79 (0.75 to 0.83)96%0.92 (0.86 to 0.96)98%0.77 (0.68 to 0.83)98%
Positive predictive value0.14 (0.13 to 0.16)75%0.24 (0.19 to 0.30)88%0.28 (0.18 to 0.41)92%0.17 (0.14 to 0.22)78%
Negative predictive value0.98 (0.98 to 0.99)46%0.95 (0.93 to 0.97)91%0.94 (0.92 to 0.95)89%0.97 (0.96 to 0.97)52%
Diagnostic OR10.77 (8.29 to 13.97)39%6.40 (5.05 to 8.10)56%5.97 (3.41 to 10.44)86%5.75 (4.59 to 7.21)0%
  • * Summary statistics consist of the pooled sensitivity, pooled specificity, positive and negative predictive values and diagnostic OR for the performance of each test in differentiating between survivors and patients who subsequently die.

  • CRB-65, confusion, respiratory rate, blood pressure, age ≥65 years; CURB, confusion, urea nitrogen, respiratory rate, blood pressure; CRB-65, confusion, respiratory rate, blood pressure, age ≥65 years; CURB, confusion, urea nitrogen, respiratory rate, blood pressure; CURB-65, confusion, urea nitrogen, respiratory rate, blood pressure, age ≥65 years; PSI, Pneumonia Severity Index.