Table 3 Risk of developing asthma or wheeze after age 17 years and risk SNPs in DPP10, ADAM33 and GPRA

Gene; SNP	Alleles		Asthma/wheeze after age 17 years	Homozygote allele 1	Heterozygote	Homozygote allele 2	2df p Value	1df p Value	OR (per allele)	95% CI for OR
Gene; SNP	1	2	Asthma/wheeze after age 17 years	n	n	n	2df p Value	1df p Value	OR (per allele)	95% CI for OR
DPP10 rs13011555	C	T	Case	173	611	509	0.180	0.066	1.09	0.99 to 1.19
DPP10 rs13011555	C	T	Control	832	3143	2820	0.180	0.066	1.09	0.99 to 1.19
DPP10 rs13392783	G	A	Case	508	608	174	0.007	0.002	1.15	1.05 to 1.25
DPP10 rs13392783	G	A	Control	2246	3028	1030	0.007	0.002	1.15	1.05 to 1.25
GPRA rs323922	G	C	Case	198	610	480	0.439	0.290	0.95	0.88 to 1.04
GPRA rs323922	G	C	Control	994	3086	2235	0.439	0.290	0.95	0.88 to 1.04
ADAM33 rs528557	C	G	Case	728	499	79	0.532	0.262	0.95	0.84 to 1.04
ADAM33 rs528557	C	G	Control	4370	2502	425	0.532	0.262	0.95	0.84 to 1.04

The 2df test relates to whether prevalence varies across the three genotypes (without an assumed genetic model). The 1df test assumes a per-allele (additive) model.
SNP, single nucleotide polymorphism.