Table 4 COPD-like symptoms in adults with asthma according to their blood inflammatory pattern
COPD-like symptomsInflammatory patternsp Value*
Non-eosinophilic pattern (n = 214)Eosinophilic pattern (n = 167)
EOSlo/NEUlo (n = 166)EOSlo/NEUhi (n = 48)p ValueEOShi/NEUlo (n = 132)EOShi/NEUhi (n = 35)p Value
Chronic cough, %19.524.40.517.721.90.60.6
Chronic phlegm, %14.220.90.312.219.30.40.6
Dyspnoea grade 3, %15.925.00.1524.442.40.040.02
  • *Non-eosinophilic vs eosinophilic (crude p value).

  • COPD, chronic obstructive pulmonary disease; EOS, eosinophils; NEU, neutrophils.