Table 4 Transmission disequilibrium test (TDT) for principal phenotypes and refined phenotypes

Gene	SNP	Families	% failed	Complete families	Allele 2 transmitted	Allele 2 not transmitted	% transmission	p Value
Principal phenotypes
SLC22A5	rs14701	658	5.6	554	139	129	51.9	0.54
IL13	rs1800925	659	4.1	582	162	177	47.8	0.42
IL13	rs1295686	660	3.3	598	197	177	52.7	0.30
IL13	rs20541	673	2.4	625	200	191	51.2	0.65
IL4	rs2243250	660	2.7	604	154	132	53.8	0.19
IL4	rs2070874	658	4.8	566	142	121	54.0	0.20
IL4	rs2243270	659	4.3	577	160	133	54.6	0.11

Refined phenotypes
SLC22A5	rs14701	462	6.1	385	101	87	53.7	0.31
IL13	rs1800925	461	3.7	412	121	128	48.6	0.66
IL13	rs1295686	461	2.9	423	139	130	51.7	0.58
IL13	rs20541	473	2.2	442	139	138	50.2	0.95
IL4	rs2243250	461	2.9	419	117	95	55.2	0.13
IL4	rs2070874	461	5.3	393	107	83	56.3	0.08
IL4	rs2243270	462	4.5	402	120	94	56.1	0.08

Cross-block haplotype rs20541(T)-rs2070874(T)		362	0.0	362	64	44	59.3	0.05