Table 3 Refined phenotype
GeneSNPCasesControlsGenotype associationAllele association
Total% failedFreqTotal% failedFreqχ2 2dfχ2 p ValueOdds ratioχ2 1dfχ2 p Value
AGMCSFrs77275442186.90.4157613.00.451.680.4320.85 (0.68–1.08)1.610.205
SLC22A5rs2745492182.80.175762.60.132.920.2321.29 (0.95–1.76)2.380.123
SLC22A5rs147012181.40.165763.60.134.240.1201.31 (0.96–1.79)2.720.099
IL13rs18009252182.30.175764.90.213.470.1760.78 (0.59–1.05)2.460.117
IL13rs12956862181.40.195762.60.180.170.9201.06 (0.8–1.41)0.090.759
IL13rs205412180.50.185766.80.151.650.4391.21 (0.9–1.62)1.370.242
CNS-1rs22433022182.30.095762.80.135.340.0690.66 (0.46–0.96)4.410.036
IL4rs22432502183.70.175765.20.1111.770.0031.64 (1.2–2.25)9.190.002
IL4rs20708742182.30.175766.80.1210.520.0051.54 (1.13–2.1)7.040.008
IL4rs7342442187.30.175765.20.128.260.0161.54 (1.12–2.12)6.590.010
IL4rs22272842185.50.285768.20.227.490.0241.37 (1.06–1.78)5.510.019
IL4rs22432682180.50.175762.10.125.550.0621.43 (1.05–1.94)4.810.028
IL4rs22432702184.60.195764.70.1312.190.0021.6 (1.19–2.17)9.000.003
BSLC22A5rs147014082.90.1710453.60.144.700.0961.20 (0.96–1.51)2.430.119
IL13rs18009254082.20.1910453.40.190.390.8231.00 (0.81–1.23)0.000.961
IL13rs12956864080.70.2110451.90.182.650.2661.18 (0.96–1.45)2.350.126
IL13rs205414083.90.2010456.10.164.780.0921.27 (1.02–1.57)4.550.033
IL4rs22432504082.90.1810443.90.1312.050.0021.48 (1.18–1.85)11.390.0007
IL4rs20708744083.20.1710454.20.138.630.0131.39 (1.11–1.74)7.770.005
IL4rs22432704086.60.1810454.70.148.540.0141.38 (1.10–1.72)7.550.006
  • Single SNP association statistics for all SNPs with positive findings and those used in haplotype analysis: (A) Cohort 1. (B) Total cohort. Association statistics for all 48 htSNPs genotyped in cohort 1 are available in table 2B in the online supplement.

  • Freq, frequency.