| Baseline | Intervention | Control | Difference (95% CI) | p Value | |
| SGRQ | |||||
| Intention-to-treat (n = 41) | (n = 23) | (n = 18) | |||
| Activity | 73.4 | 70.4 | 78.7 | 8.3 (−17.3 to 0.5) | 0.06 |
| Impacts | 43.5 | 35.4 | 52.8 | 17.4 (−28.8 to −6.1) | 0.004 |
| Symptoms | 60.6 | 59.5 | 61.6 | 2.1 (−14.4 to 10.3) | 0.73 |
| Total | 55.3 | 51.2 | 61.3 | 10.1 (−18.5 to −1.7) | 0.02 |
| Completed study (n = 37) | |||||
| 6 months | (n = 20) | (n = 17) | |||
| Activity | 74.8 | 67.0 (3.3) | 80.4 (3.5) | 13.4 (−23.3 to −3.6) | 0.009 |
| Impacts | 46.1 | 42.3 (2.8) | 48.5 (3.0) | 6.2 (−14.5 to 2.2) | 0.14 |
| Symptoms | 62.8 | 63.2 (2.4) | 66.6 (2.5) | 3.4 (−10.4 to 3.7) | 0.34 |
| Total | 57.6 | 53.4 (2.2) | 61.1 (2.4) | 7.7 (−14.4 to −1.1) | 0.02 |
| 12 months | |||||
| Activity | 75.4 | 69.3 (2.9)† | 80.5 (3.0) | 11.2 (−19.8 to −2.7) | 0.01 |
| Impacts | 47.0 | 35.8 (3.3)† | 53.7 (3.5)‡ | 17.9 (−27.6 to −8.2) | 0.001 |
| Symptoms | 62.8 | 63.4 (4.4)† | 63.8 (4.5) | 0.4 (−13.3 to 12.5) | 0.95 |
| Total | 58.2 | 50.6 (2.7)† | 63.9 (2.8)‡ | 13.3 (−21.3 to −5.4) | 0.002 |
| Short Form-36 | |||||
| Intention-to-treat (n = 41) | (n = 23) | (n = 18) | |||
| Health change | 34.8 | 51.7 (5.6) | 32.5 (6.4) | 19.2 (2.0 to 36.4) | 0.029 |
| Completed study (n = 37) | |||||
| 6 months | (n = 19)§ | (n = 17) | |||
| Health change | 35.4 | 53.8 (4.8) | 29.6 (5.0) | 24.2 (10.1 to 38.3) | 0.001 |
| 12 months | (n = 18)¶ | (n = 16)¶ | |||
| Health change | 33.8 | 55.2 (5.7) | 28.5 (6.1) | 26.7 (9.7 to 43.7) | 0.003 |
Values are adjusted for baseline measurements and expressed as means (SE); Difference: difference in measurements between intervention and control groups; 95% confidence interval (CI) for the difference between intervention and control groups; p values for ANCOVA tests between intervention and control groups.
St George’s Respiratory Questionnaire (SGRQ): scores range from 0 (perfect health) to 100 (worst possible health);†n = 18 (two patients refused to complete SGRQ at 12 months); ‡n = 16 (one patient failed to complete the Impacts section of SGRQ at 12 months).
SF-36: scores range from 0 (worst possible health) to 100 (perfect heath); §one patient refused to complete the SF-36 at 6 months and another at 12 months; ¶two patients refused to complete the SF-36 at 12 months.