Table 1 Baseline data comparing patients who completed the study with those who did not (n = 59)
Completed(n = 37)Withdrew or died(n = 22)p Value*
Demographic data
    Gender (M:F)18:1912:10
    Age (years)69.0 (47–85)69.1 (46–89)0.97
    Weight (kg)53.9 (8.2)54.4 (7.4)0.82
    BMI (kg/m2)19.9 (1.6)19.5 (1.6)0.38
    Unintentional change from usual weight (kg)−8.7 (6.0)−8.6 (5.6)0.93
    % fat mass23.3 (6.2)†21.5 (7.7)0.35
Smoking status and respiratory function
    Ex-smokers20 (54%)12 (55%)
    Smokers14 (38%)10 (45%)0.37
    Non-smokers3 (8%)0 (0%)
    FEV1 (% predicted)31.9 (12.5)31.7 (14.4)0.95
    FEV1/FVC0.44 (0.14)0.44 (0.13)0.91
    MRC dyspnoea score3 (1–5)4 (1–5)0.16
Nutrient intake (diet history method)
    Energy (kcal/day)2015 (406)1850 (360)0.11
    Protein (g/day)68.3 (11.9)65.9 (11.1)0.44
Quality of life and functional status
    SGRQ Total Score57.1 (3.2)60.8 (3.8)0.68
    ADL score12 (7–18)12 (8–18)0.93
  • Values are mean (range) for age, mean (SD) for weight, BMI, unintentional weight change, % fat mass, FEV1 (% predicted), FEV1/FVC, nutrient intake, SGRQ Total score and ADL score and number (%) patients for smoking status.

  • *p values for unpaired t tests for age, weight, body mass index, FEV1, FEV1/FVC, nutrient intake and SGRQ total score, χ2 test for smoking status and Mann-Whitney test for MRC dyspnoea and ADL scores.

  • †n = 36 as one patient did not consent to measurement.

  • ADL, Activities of Daily Living; BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; SGRQ, MRC, Medical Research Council; St George’s Respiratory Questionnaire.