| LTOT(n = 72) | NIV+LTOT(n = 72) | |
| Age (years) | 68.8 (67.1 to 70.5) | 67.2 (65.3 to 69.1) |
| Gender (% male) | 61% | 69% |
| BMI (kg/m2) | 25.4 (24.0 to 26.8) | 25.5 (24.3 to 26.7) |
| FEV1.0 (litres) | 0.55 (0.51 to 0.59) | 0.63 (0.57 to 0.69) |
| FEV1.0 (% predicted) | 23.1 (21.4 to 24.8) | 25 (22.4 to 27.6) |
| FVC (litres) | 1.76 (1.60 to 1.92) | 1.98 (1.80 to 2.16) |
| FVC (% predicted) | 54.8 (51.0 to 58.6) | 57.5 (53.9 to 61.1) |
| FEV1.0/FVC (%) | 32.9 (30.9 to 34.9) | 32.9 (30.3 to 35.5) |
| Tlco (ml/min/mmHg) | 6.76 (5.96 to 7.56) | 8.61 (7.49 to 9.73) |
| Tlco (% predicted) | 30.7 (27.9 to 33.5) | 37.2 (33.2 to 41.2) |
| Oxygen treatment (h/day) | 20.5 (19.5 to 21.5) | 20 (18.8 to 21.2) |
| Pao2 (mm Hg, air) | 52.5 (50.1 to 54.9) (n = 62) | 54.8 (52.4 to 57.2) (n = 61) |
| Paco2 (mm Hg, air) | 54.4 (52.6 to 56.2) (n = 62) | 52.6 (51.0 to 54.2) (n = 61) |
| SGRQ | 64.1 (49.9–70.8)* | 69 (57.2–77.2)* |
Values are mean (95% CI) or *median (interquartile range).
BMI, body mass index; FEV1.0, forced expiratory volume in 1 s; FVC, forced vital capacity; LTOT, long-term oxygen therapy; NIV + LTOT, nocturnal non-invasive ventilation plus long-term oxygen therapy; Pao2, Paco2, arterial oxygen and carbon dioxide tensions; SGRQ, St George Respiratory Questionnaire; Tlco, single breath lung transfer factor for carbon monoxide.