| Positive biopsy(n = 39) | Negative biopsy(n = 38) | p Value | |
| Mean (SD) age (years) | 45 (13) | 39 (12) | 0.05 |
| Female gender, n (%) | 26 (66.7) | 12 (31.6) | 0.003 |
| Ever smoked, n (%) | 13 (33.3) | 21 (55.2) | 0.05 |
| FEV1 (% predicted)* | 88.4 (22.6) | 91.4 (15.5) | 0.60 |
| FVC (% predicted)* | 87.6 (18.9) | 93.8 (12.0) | 0.24 |
| Tlco (% predicted)† | 75.5 (19.0) | 84.5 (14.7) | 0.04 |
| BAL % lymphocytes‡ | 29.4 (10.9, 40.5) | 12.3 (7.3, 22.8) | 0.05 |
| BAL % neutrophils‡ | 0.7 (0.4, 2.1) | 1.6 (0.9, 3.1) | 0.02 |
| BAL % eosinophils‡ | 0.5 (0.2, 1.2) | 0.3 (0.1, 0.9) | 0.24 |
| BAL % macrophages‡ | 60 (53, 72) | 79 (57, 86) | 0.03 |
Demographic and lung function data presented as mean (SD). BAL data presented as median (interquartile range).
*FEV1/FVC data available for 75 patients. †Tlco data available for 66 patients. ‡BAL data available for 59 patients.
BAL, bronchoalveolar lavage; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; TBB, transbronchial biopsy; Tlco, carbon monoxide transfer factor.