Table 1

Design of the COPE II study, including the two interventions (self-treatment of exacerbations and COPE-active) and the measurements at baseline, 7 and 12 months

Time scheduleInterventionsSelf-treatment group (intervention group)Control group
Subgroup 1Subgroup 2Subgroup 3Subgroup 4
Month 0Baseline measurement××××
Month 1Self-management courses××××
Month 1–12Self-treatment of exacerbations××
Month 2–7COPE-active: “compulsory”××
Month 7Measurement××××
Month 8–12COPE-active: “voluntary”××
Month 12Measurement××××