Univariable and multivariable analysis for the association between characteristics of tuberculosis cases and extrapulmonary site of disease
| Number | Univariable | Multivariable* | |||
| EP | All | OR (95% CI) | OR (95% CI) | p Value | |
| Year | |||||
| 1999 | 2717 | 5704 | Reference | Reference | 0.001 |
| 2000 | 2966 | 6271 | 0.98 (0.91 to 1.05) | 1.00 (0.92 to 1.09) | |
| 2001 | 3058 | 6597 | 0.95 (0.88 to 1.02) | 0.95 (0.87 to 1.03) | |
| 2002 | 3181 | 6794 | 0.98 (0.91 to 1.05) | 0.89 (0.81 to 0.97) | |
| 2003 | 3359 | 6913 | 1.03 (0.96 to 1.11) | 0.95 (0.87 to 1.03) | |
| 2004 | 3600 | 7240 | 1.09 (1.01 to 1.16) | 1.01 (0.92 to 1.10) | |
| 2005 | 4188 | 8037 | 1.19 (1.11 to 1.27) | 1.03 (0.95 to 1.12) | |
| 2006 | 4205 | 8051 | 1.21 (1.13 to 1.29) | 1.06 (0.97 to 1.15) | |
| Gender | |||||
| Male | 13877 | 30380 | Reference | Reference | <0.001 |
| Female | 13343 | 25121 | 1.36 (1.31 to 1.40) | 1.27 (1.21 to 1.32) | |
| Age group | |||||
| 0–14 | 1502 | 3209 | 0.90 (0.84 to 0.97) | 1.18 (1.08 to 1.30) | |
| 15–29 | 8219 | 16391 | Reference | Reference | <0.001 |
| 30–44 | 8730 | 15732 | 1.25 (1.19 to 1.30) | 1.39 (1.32 to 1.47) | |
| 45–59 | 4212 | 8570 | 0.97 (0.92 to 1.02) | 1.32 (1.23 to 1.42) | |
| 60+ | 4602 | 11690 | 0.64 (0.61 to 0.68) | 1.06 (0.99 to 1.14) | |
| Place of birth | |||||
| Born in UK | 5176 | 15658 | Reference | Reference | <0.001 |
| Born abroad, entry <1 year ago | 1006 | 2757 | 1.17 (1.07 to 1.27) | 0.74 (0.67 to 0.83) | |
| Born abroad, entry 1–2 years ago | 2191 | 3818 | 2.72 (2.53 to 2.92) | 1.67 (1.52 to 1.83) | |
| Born abroad, entry 2–5 years ago | 4644 | 7583 | 3.21 (3.03 to 3.40) | 1.90 (1.75 to 2.05) | |
| Born abroad, entry 5–10 years ago | 2719 | 4497 | 3.11 (2.91 to 3.34) | 1.75 (1.60 to 1.92) | |
| Born abroad, entry 10+ years ago | 5350 | 9134 | 2.90 (2.75 to 3.06) | 1.48 (1.37 to 1.60) | |
| Born abroad, year entry missing | 3185 | 5773 | 2.54 (2.38 to 2.70) | 1.43 (1.32 to 1.56) | |
| Ethnic group | |||||
| White | 3871 | 14042 | Reference | Reference | <0.001 |
| Black African | 6095 | 11412 | 3.04 (2.89 to 3.20) | 1.99 (1.83 to 2.17) | |
| Indian, Pakistani, Bangladeshi | 12395 | 20212 | 4.24 (4.05 to 4.45) | 3.09 (2.87 to 3.32) | |
| Other | 3646 | 7269 | 2.67 (2.52 to 2.83) | 1.88 (1.73 to 2.05) | |
| Region of reporting | |||||
| Other | 14983 | 31936 | Reference | Reference | 0.092 |
| London | 12291 | 23671 | 1.22 (1.18 to 1.26) | 1.04 (0.99 to 1.09) | |
| Previous TB diagnosis | |||||
| No | 20163 | 40287 | Reference | Reference | <0.001 |
| Yes | 1568 | 3985 | 0.65 (0.60 to 0.69) | 0.72 (0.67 to 0.78) | |
| HIV co-infection† | |||||
| No/unknown | 26015 | 53005 | Reference | ||
| Yes | 1259 | 2602 | 1.00 (0.92 to 1.08) | ||
*Overall p value for categorical variables.
†For cases reported between 1999 and 2005.
EP, extrapulmonary, OR, odds ratio; TB, tuberculosis.