Table 4 Modelled effect of exclusive use of ETA or BAL on the reported incidence of VAP, using the numbers of clinically suspected VAP episodes from infection surveillance occurring in the ICU over 12 months (fig 2; n = 110)
BAL mean estimate (95% CI)Qualitative ETA mean estimate (95% CI)Quantitative ETA mean estimate (95% CI)
Positive culture23 (11 to 35)96 (85 to 106)56 (41 to 69)
Negative culture87 (75 to 99)14 (4 to 25)54 (41 to 69)
Proportion of “clinically suspected VAPs” reported as “confirmed VAP”21% (10 to 32%)87% (77 to 96%)51% (37 to 63%)
Cases/1000 ventilator days6.1 (2.9 to 9.2)25.5 (22.5 to 28.1)15.0 (11.0 to 18.3)
  • Numbers show mean estimate and upper and lower confidence limit using 95% CIs for proportions (z test) and were derived using the data from fig 1.

  • BAL, bronchoalveolar lavage; ETA, endotracheal aspirate; ICU, Intensive Care Unit; VAP, ventilator-associated pneumonia.