Healthy(n = 26) | COPD(n = 30) | p Value | |
Age (years) | 63 (9) | 68 (9) | 0.093 |
Sex (M:F) | 11:15 | 16:14 | 0.579* |
Weight (kg) | 70.4 (11.8) | 72.6 (15.8) | 0.562 |
BMI (kg/m2) | 25.0 (3.5) | 26.0 (4.5) | 0.348 |
FFM (kg) | 46.9 (9.3) | 46.1 (7.3) | 0.730 |
FFMI (kg/m2) | 16.5 (1.8) | 16.7 (2.0) | 0.616 |
Smoking (pack-years) | 14 (14) | 45 (30–50) | <0.001† |
FEV1 (l) | 2.85 (0.67) | 1.09 (0.78–1.51) | <0.001† |
FEV1 (% predicted) | 109 (14) | 48 (28–69) | <0.001† |
Sao2 (%) | 98 (1) | 95 (2) | <0.001 |
Data are mean (SD) or median (interquartile range) where appropriate.
p Values derived from unpaired t tests, χ2 test with Yates’ continuity correction (indicated by *) or the Mann-Witney test (indicated by †).
BMI, body mass index; FFM, fat-free mass; FFMI, fat-free mass index; FEV1, forced expiratory volume in 1 s; Sao2, resting peripheral oxygen saturation measured by pulse oximetry.