Table 1 Characteristics of the 123 patients with resected stage I non-small cell lung cancer with local recurrence
VariablesPattern of local recurrence
Local onlyLocal and distant
No of patients (%)No of patients (%)
Total No of patients74 (60.2)49 (39.8)
Age at recurrence (years) (mean (SD))64.5 (9.9)65.5 (7.9)
Sex
    Male65 (87.8)41 (83.7)
    Female9 (12.2)8 (16.3)
Smoking index (pack-years) (median (IQR))30.0 (16.3–40.0)30.0 (10.8–40.0)
Tumour location
    Right lung51 (68.9)41 (83.7)
    Left lung23 (31.1)8 (16.3)
Tumour size (cm) (mean (SD))4.1 (2.2)4.4 (2.3)
Histological type
    Squamous cell carcinoma41 (55.4)19 (38.8)
    Adenocarcinoma24 (32.4)21 (42.8)
    Bronchioalveolar carcinoma6 (8.1)4 (8.2)
    Large cell carcinoma3 (4.1)4 (8.2)
    Adenosquamous carcinoma0 (0.0)1 (2.0)
Extent of pulmonary resection
    Sublobar resection10 (13.5)1 (2.0)
    Lobectomy or bilobectomy54 (73.0)45 (91.8)
    Pneumonectomy10 (13.5)3 (6.2)
T status
    T127 (36.5)11 (22.4)
    T247 (63.5)38 (77.6)
Visceral pleural invasion
    Absent56 (75.7)44 (89.8)
    Present15 (20.2)4 (8.2)
    Unknown3 (4.1)1 (2.0)
No of LNs dissected (mean (SD))12.0 (8.3)16.1 (12.4)
    LN⩽1551 (68.9)27 (55.1)
    LN>1520 (27.0)21 (42.9)
    Unknown3 (4.1)1 (2.0)
Disease free interval (months) (mean (SD))18.4 (12.0)18.0 (15.6)
    ⩽1840 (54.1)30 (61.2)
    >1834 (45.9)19 (38.8)
Mediastinal recurrence
    Absent38 (51.4)32 (65.3)
    Present18 (24.3)12 (24.5)
    Unknown18 (24.3)5 (10.2)
Treatment for recurrence
    None7 (9.5)9 (18.4)
    With surgery8 (10.8)2 (4.1)
        Surgery only60
        Surgery + C/T and/or R/T22
    C/T and/or R/T26 (35.1)27 (55.1)
        C/T only99
        R/T only119
        C/T + R/T69
    Unknown33 (44.6)11 (22.4)
  • C/T, chemotherapy; IQR, interquartile range; LN, lymph node; R/T, radiotherapy.