| Control subjects (n = 7) | COPD patients (n = 15) | |
| Age (years) | 62 (6) | 62 (7) |
| BMI (kg/m2) | 27.9 (5.1) | 24.4 (6.2) |
| FFMI (kg/m2) | 22.3 (2.5) | 20.0 (3.5) |
| FEV1 (l) | 3.2 (0.5) | 1.4 (0.6)*** |
| FEV1 (% pred) | 95 (15) | 41 (18)*** |
| FVC (% pred) | 97 (12) | 68 (18)*** |
| FEV1/FVC (%) | 78 (5) | 44 (12)*** |
| RV (% pred) | NA | 177 (48) |
| Tlco (% pred) | NA | 50 (21) |
| Pao2 (kPa) | 12.6 (1.7) | 9.9 (1.3)* |
| Paco2 (kPa) | 4.9 (0.5) | 5.6 (0.8) |
| Q isometric (Nm) | 205 (31) | 153 (58)* |
| Q isokinetic (Nm) | 129 (30) | 92 (43)* |
| Q endurance (J) | 2200 (599) | 1480 (725)** |
| Vo2peak (% pred) | 100 (16) | 57 (30)* |
| WRpeak (% pred) | 100 (18) | 48 (25)* |
Data are presented as mean (SD).
BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FEV1/FVC, FEV1/FVC ratio expressed as actual percentage; FFMI, fat free mass index; FVC, forced vital capacity; J, Jules; NA, not available; Nm, Newton metres; Paco2, arterial carbon dioxide tension; Pao2, arterial oxygen tension; pred, predicted; Q, quadriceps force; RV, residual volume; Tlco, carbon monoxide transfer factor; Vo2peak, peak exercise oxygen uptake; WRpeak, peak work rate.
*p⩽0.05, **p = 0.06, ***p⩽0.001 between patients with COPD and control subjects.