| Subtherapeutic CPAP | Therapeutic CPAP | Difference in change (95% CI of difference) | p Value* | |||
| Baseline | Follow up | Baseline | Follow up | |||
| hsCRP (mg/l) | 2.68 (1.27–4.49) | 3.12 (1.33–6.11) | 3.05 (1.60–7.12) | 2.80 (1.30–5.76) | −0.24 (−0.88 to +0.24) | 0.30 |
| hsCRP† (mg/l) | 2.64 (1.17–3.61) | 2.83 (1.02–3.91) | 2.36 (1.24–3.61) | 2.03 (1.13–4.45) | –0.10 (−0.64 to +0.30) | 0.49 |
| IL6 (pg/ml) | 5.13 (2.89–9.38) | 5.51 (3.26–7.61) | 4.45 (2.13–10.01) | 4.82 (2.24–10.96) | +0.52 (−0.72 to +1.94) | 0.45 |
| IL6† (pg/ml) | 4.61 (2.53–7.08) | 4.19 (2.81–7.42) | 3.47 (2.10–8.93) | 3.98 (2.23–9.54) | +0.35 (−0.73 to +1.60) | 0.61 |
| IFNγ (pg/ml) | 3.37 (0.83–5.87) | 4.22 (0.81–6.43) | 3.28 (0.49–5.72) | 3.37 (0.49–6.67) | −0.07 (−0.81 to +0.44) | 0.82 |
| IFNγ† (pg/ml) | 3.40 (0.71–5.99) | 4.23 (0.72–7.31) | 3.16 (0.52–5.11) | 3.70 (0.51–5.92) | +0.06 (−0.59 to +0.92) | 0.74 |
| Adiponectin (µg/ml) | 5.80 (3.81–7.35) | 5.62 (4.23–7.88) | 4.71 (2.74–8.21) | 4.60 (2.92–7.86) | +0.05 (−0.36 to +0.47) | 0.84 |
Values are medians (interquartile range).
95% CI, 95% confidence intervals for difference between median changes.
*p value for comparisons of median changes between groups.
†Subjects with hsCRP values >8 mg/l excluded.
CPAP, continuous positive airway pressure; hsCRP, highly sensitive C reactive protein; IFNγ, interferon γ; IL, interleukin.