Abstract S86 Table
VariableBronchodilator response group
ABC
No of patients at baseline333822
FEV1 % predicted59.09 (4.03)58.38 (3.03)74.65 (4.29)*†
FEV1 : FVC0.47 (0.02)0.45 (0.02)0.51 (0.02)
KCO % predicted90.24 (5.19)90.42 (5.21)94.86 (6.79)
Visible emphysema (at baseline)44.6%65.1%50%
UZVI26.91 (3.08)28.32 (2.83)28.00 (2.94)
LZVI25.51 (3.02)27.83 (2.24)28.96 (3.00)
Change in FEV1 (ml/year)−29.88 (16.28)−25.26 (9.42)−67.35 (19.18)†
Change in FEV1 (% predicted/year)−0.705 (0.808)−0.604 (0.396)−1.989 (0.928)
Change in FEV1 : FVC (%/year)−4.01 (4.99)−2.32 (2.27)−5.10 (3.05)
Change in KCO (% predicted/year)−2.75 (0.83)†−0.77 (0.59)*−0.02 (0.61)*
Change in UZVI (%/year)+1.23 (0.74)+0.37 (0.47)−0.28 (0.59)
Change in LZVI (%/year)+1.16 (0.47)+0.52 (0.43)−0.62 (0.89)*
  • Post-bronchodilator lung function values and voxel indices are from baseline and expressed as mean (standard error). *Significant difference (p<0.05) from group A; †Significant difference (p<0.05) from group B; LZVI, lower zone voxel index (−910 Hounsfield units); UZVI, upper zone voxel index (−910 Hounsfield units).