Table 2 Measurements before and 20 min after salbutamol in children with asthma compared with healthy controls
Healthy controlsAsthmatic children
Pre-salbutamolPost-salbutamolp Value (post-salbutamol vs pre-salbutamol)
Mean (SD) FEV1 z-score−0.69 (0.88)−1.26 (1.25)−0.93 (0.23)0.03
Mean (SD) LCI6.24 (0.47)6.82 (1.04)6.64 (0.69)*0.12
Mean (SD) Scond0.017 (0.02)0.027 (0.02)0.020 (0.04)0.19
Mean (SD) Sacin0.12 (0.06)0.12 (0.06)0.14 (0.10)0.45
  • FEV1, forced expiratory volume in 1 s; LCI, lung clearance index; Sacin, Scond, phase III (alveolar) slope of the acinar and conductive airways, respectively.

  • *Significant difference in post-salbutamol value compared with healthy controls (p = 0.01).