Healthy controls | Asthmatic children | |||
Pre-salbutamol | Post-salbutamol | p Value (post-salbutamol vs pre-salbutamol) | ||
Mean (SD) FEV1 z-score | −0.69 (0.88) | −1.26 (1.25) | −0.93 (0.23) | 0.03 |
Mean (SD) LCI | 6.24 (0.47) | 6.82 (1.04) | 6.64 (0.69)* | 0.12 |
Mean (SD) Scond | 0.017 (0.02) | 0.027 (0.02) | 0.020 (0.04) | 0.19 |
Mean (SD) Sacin | 0.12 (0.06) | 0.12 (0.06) | 0.14 (0.10) | 0.45 |
FEV1, forced expiratory volume in 1 s; LCI, lung clearance index; Sacin, Scond, phase III (alveolar) slope of the acinar and conductive airways, respectively.
*Significant difference in post-salbutamol value compared with healthy controls (p = 0.01).