Table 2 Anthropometric and pulmonary function data and CT measured parameters in each of the COPD subgroups (n = 165)
NCT (n = 41)AD (n = 24)ED (n = 81)Mixed (n = 19)
Age (years)70 (7)70 (9)71 (7)70 (6)
Smoking Index (pack-years)70 (44)72 (44)69 (27)84 (55)
Height (cm)163 (7)161 (7)163 (6)159 (6)
Weight (kg)61 (9)60 (9)54 (8)*†53 (6)*
BMI (kg/ m2)22.9 (2.1)23.0 (2.6)20.2 (2.8)*†21.0 (2.8)*
BSA (m2)1.65 (0.15)1.61 (0.14)1.58 (0.12)1.54 (0.10)
FVC (%predicted)72 (17)64 (17)76 (19)†68 (14)
FEV1 (%predicted)54 (18)44 (17)43 (18)*36 (13)*
FEV1/FVC (%)50 (12)48 (11)38 (10)*†37 (10)*†
RV/TLC (%)45 (9)50 (11)48 (9)51 (7)
Tlco (mmol/min/kPa/l)1.27 (0.39)1.52 (0.45)0.85 (0.30)*†1.00 (0.33)*†
WA% (%)61.9 (4.0)74.2 (4.2)*61.0 (4.7)†71.8 (3.7)*‡
LAA% (%)21.1 (7.5)19.6 (6.5)47.2 (10.2)*†45.7 (6.5)*†
  • Values are mean (SD).

  • Smoking Index  =  (the average number of packs smoked/day (20 cigarettes/pack) × years of smoking).

  • AD, airway dominant; BMI, body mass index; BSA, body surface area; COPD, chronic obstructive pulmonary disease; ED, emphysema dominant; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LAA%, percentage of low attenuation area; NCT, normal by CT; RV, residual volume; TLC, total lung capacity; Tlco, carbon monoxide transfer coefficient; WA%, percentage of the wall area.

  • *p<0.05 versus NCT; †p<0.05 versus AD; ‡p<0.05 versus ED.