Abstract P12 Table Endpoints at the start and end of the exacerbation for each group

Variable	Exacerbation start (PA) N = 19	End exacerbation (PA) N = 19	p Value	Start exacerbation (other PPM) N = 13	End exacerbation (other PPM) N = 13	p Value
24-h Sputum volume (ml)	24.3 ± 22.0	6.1 ± 5.3	0.005	39.5 ± 19.4	11.3 ± 10.8	0.001
FEV₁ (l)	1.52 ± 0.61	1.53 ± 0.58	0.9	1.32 ± 0.48	1.51 ± 0.61	0.01
FVC (l)	2.38 ± 0.88	2.44 ± 0.81	0.3	2.25 ± 0.62	2.58 ± 0.96	0.02
Exercise capacity (m)	226 ± 161	285 ± 177	<0.001	188 ± 184	234 ± 198	0.03
ESR (mm/h)	36.8 ± 30.0	21.2 ± 13	<0.001	47.5 ± 26.2	22.7 ± 16.4	0.02
CRP (mg/l)	49.7 ± 72.4	4.8 ± 4.1	0.02	91.9 ± 62.6	11.1 ± 16.7	<0.001
WCC (×10⁹) (range 4–11)	10.2 ± 3.6	6.5 ± 1.8	<0.001	12.2 ± 3.7	8.3 ± 3.0	0.01
LCQ (total score)	12.0 ± 2.6	16.9 ± 2.8	<0.001	10.8 ± 3.5	16.0 ± 4.2	0.001
SGRQ (total score)	56.7 ± 16.7	46.9 ± 19.7	<0.001	59.5 ± 19.1	44.2 ± 21.1	<0.001
No of patients with pathogens	19/19	7/19	<0.001	13/13	0/13	<0.001

CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; LCQ, Leicester cough questionnaire; PA, P aeruginosa; PPM, potential pathogenic organisms; SGRQ, St George’s respiratory questionnaire; WCC, white cell count.