Subjects at risk at baseline (n) | New asthma reports | p Value for difference | |
Baseline BHR | |||
Without BHR | 3800 | 94/2.5% | |
With BHR | 626 | 50/8.0% | <0.001 |
GSTP1 Ile105Val | |||
Ile/Val or Val/Val | 2355 | 60/2.6% | |
Ile/Ile | 2071 | 77/4.0% | 0.005 |
GSTM1 | |||
No deletion | 2100 | 71/3.4% | |
Deletion | 2322 | 73/3.1% | 0.66 |
GSTT1 | |||
No deletion | 3600 | 119/3.3% | |
Deletion | 822 | 25/3.0% | 0.70 |
BHR, bronchial hyperresponsiveness; GST, glutathione S-transferase.