Table 1 Characteristics of 36 patients with pN2-NSCLC
CharacteristicNo (%)
Mean (SD) age (years)66.8 (9.4)
    <66.814 (38.9)
    >66.822 (61.1)
Sex
    Female5 (13.9)
    Male31 (86.1)
Histopathology
    Adenocarcinoma19 (52.8)
    SCC17 (47.2)
Mediastinal LN stations
    Single5 (13.9)
    Multiple31 (86.1)
Protein expressions
    pRb
        Negative13 (36.1)
        Positive23 (63.9)
    Cyclin D1
        Negative25 (69.4)
        Positive11 (30.6)
    p16
        Negative17 (47.2)
        Positive19 (52.8)
    p53
        Negative17 (47.2)
        Positive19 (52.8)
    p21
        Negative27 (75.0)
        Positive9 (25.0)
    Ki-67
        LI <20%13 (36.1)
        LI >20%23 (63.9)
Treatment response(n = 28)
    CR1 (3.5)
    PR12 (42.9)
    SD10 (35.7)
    PD5 (17.9)

  • CR, complete response; LN, lymph nodes; LI, labelling index; PD, progressive disease; PR, partial response; SCC, squamous cell carcinoma; SD, stable disease.